The Seattle Seahawks and San Francisco 49ers each come into Thursday Night Football off losses despite each being favored by a touchdown.
Seattle stumbled against the New York Giants while San Francisco collapsed to the Arizona Cardinals, making this short turnaround a tricky one for these NFC West clubs.
Oddsmakers have the Niners tabbed as 3-point road favorites heading to always-loud Lumen Field.
I investigate the opening Week 6 NFL odds for Thursday Night Football and give my early leans, predictions, and NFL picks for Seahawks at 49ers on October 10.
Check out our 49ers vs. Seahawks live blog for real-time updates ahead of kickoff.
49ers vs Seahawks predictions
Early spread lean49ers -3 (-120 at F…